VSIG1 Mouse Monoclonal Antibody [Clone ID: CT1]

Specifications

Product Data
Clone Name	CT1
Applications	FC, FN, IP
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. Identification and enumeration of ChT1+ cells. (Ref.4) Immunoprecipitation. (Ref.1,4) In vitro Inhibition of T cell differentiation. (Ref.4).
Reactivity	Chicken
Host	Mouse
Clonality	Monoclonal
Immunogen	Chicken thymocytes.
Specificity	This antibody is specific to ChT1 antigen (Mr 63/104 kDa) on Chicken thymocyte. (Ref.1) CT1 can block T cell differentiation in vitro, in thymic organ cultures and in thymocyte precursors cultured on stromal cell monolayers. (Ref.4) CT1 also recognizes quail cortical thymocytes. (Ref.1)
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	V-set and immunoglobulin domain containing 1
Database Link	Entrez Gene 414795 Chicken UniProt ID Q9PWR4
Background	ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens, about 90% of the thymocytes as well as a subpopulation of peripheral lymphocytes (which represent recent thymic emigrants) are ChT1 positive. (Ref.1-4) Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. (Ref.3)
Synonyms	Cell surface A33 antigen, Glycoprotein A34, GPA34
Reference Data

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