CD8A Mouse Monoclonal Antibody [Clone ID: fCD8]

Specifications

Product Data
Clone Name	fCD8
Applications	FC
Recommend Dilution	Flow Cytometry: 1 µg/10e6 cells. (Ref.1-2) Immunohistochemistry on frozen tissue sections. Immunoprecipitation.
Reactivity	Feline
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes Feline CD8 (Mr. 70 kDa) (38/31 kDa under reducing conditions).
Formulation	PBS/NaN3 Label: Biotin State: Liquid purified Ig fraction
Concentration	lot specific
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	UniProt ID P41688
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms	CD8 alpha chain, CD8A, MAL
Note	U.S. Patent 4,520,110; European Patent No. 76,695; and Canadian Patent No. 1,179,942. FACScanTM is a registered trademark of Becton Dickinson Immunocytometry Systems, Inc., San Jose, CA.
Reference Data

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