RLA-DQ Mouse Monoclonal Antibody [Clone ID: 2C4]

Specifications

Product Data
Clone Name	2C4
Applications	FC, IHC, IP
Recommend Dilution	Flow Cytometry. (Ref.1,3) Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). (Ref.3,4) Immunoprecipitation. (Ref.1)
Reactivity	Rabbit
Host	Mouse
Clonality	Monoclonal
Immunogen	Rabbit spleen cells.
Specificity	This antibody is specific to Rabbit RLA-DQ alpha chain (Mr ~35 kDa). It reacts with RLA-DQ-transfected cells, but not with RLA-DR-transfected cells. (Ref.2) In normal adult rabbits, the antibody reacts with 30-60% of peripheral blood leukocytes. (Ref.2,3) It has also been reported that the antibody stains: lymphocytes and macrophages in the spleen; lymphocytes in the thymic medulla and some cells in the cortex; Kupffer cells in the liver; and synovial lining cells (i.e., infiltrating macrophages) in inflamed synovium. (Ref.4) DQ alpha transcripts have been detected in bone marrow and spleen and, to a lesser extent, in appendix, lymph nodes, and other organs. (Ref.5)
Formulation	100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Synonyms	MHC Class II RLA-DQ
Reference Data

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