Thy1 Rat Monoclonal Antibody [Clone ID: G7]

Specifications

Product Data
Clone Name	G7
Applications	FC
Recommend Dilution	Flow Cytometry. (Ref.1,10) Immunohistochemistry (Acetone-Fixed, Frozen Sections). (Ref.10) In vitro T Cell Activation. (Ref.1,5,6,9) Induction of apoptosis.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A). MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7). It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)
Formulation	PBS without preservatives. State: Low Endotoxin State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	thymus cell antigen 1, theta
Database Link	Entrez Gene 21838 Mouse UniProt ID P01831
Background	CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2)
Synonyms	Thy-1, THY1, CDw90
Reference Data

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