Cd38 Rat Monoclonal Antibody [Clone ID: NIMR-5]

CAT#: AM08041LE-N

Cd38 rat monoclonal antibody, clone NIMR-5, Low Endotoxin



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CNY 5,533.00


货期*
4周

规格
    • 500 ug

Product images

Specifications

Product Data
Clone Name NIMR-5
Applications FC, FN, IHC, IP
Recommend Dilution Flow Cytometry. (Ref.1-8)
Immunoprecipitation. (Ref.1)
Immunohistochemistry on Frozen Sections. (Ref.7)
Functional Assay: Induction of B lymphocyte proliferation. (Ref.3-8)
Reactivity Mouse
Host Rat
Clonality Monoclonal
Specificity This antibody is specific to CD38 (Mr. 42-46 kDa).
Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. (Ref.1-8)
Formulation PBS containing no preservatives.
State: Low Endotoxin
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Gene Name CD38 antigen
Background Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing Nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRalphabeta+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.
Synonyms cADPr hydrolase 1, T10
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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