Cd28 Hamster Monoclonal Antibody [Clone ID: PV-1]

Specifications

Product Data
Clone Name	PV-1
Applications	FC
Recommend Dilution	Flow Cytometry: < / = 3 µg/10e6 cells. (Ref.8-10)
Reactivity	Mouse
Host	Hamster
Clonality	Monoclonal
Specificity	This antibody is specific to Murine CD28.
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	CD28 antigen
Database Link	Entrez Gene 12487 Mouse UniProt ID P31041
Background	CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4) CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. (Ref.5) CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.6-9)
Synonyms	TP44
Reference Data

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