Cd24a Rat Monoclonal Antibody [Clone ID: 91]

Specifications

Product Data
Clone Name	91
Applications	FC, IHC, IP
Recommend Dilution	Flow Cytometry: < / = 2 µg/10e6 cells. (Ref.8)
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).
Formulation	PBS containing 0.09% Sodium Azide as preservative. Label: Biotin State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD24a antigen
Database Link	Entrez Gene 12484 Mouse UniProt ID P24807
Background	CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3). The monoclonal antibody 91 can be used to inhibit B-cell differentiation. (Ref.8)
Synonyms	X62 heat stable antigen, HSA
Reference Data

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