Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: 8A12]

Specifications

Product Data
Clone Name	8A12
Applications	ELISA, FC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500-1/2000. Flow Cytometry: 1/200-1/400.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human KLK3 expressed in E. Coli.
Specificity	This antibody reacts to KLK3.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	kallikrein related peptidase 3
Database Link	Entrez Gene 354 Human UniProt ID P07288
Background	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Synonyms	Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
Reference Data

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