PDX1 Mouse Monoclonal Antibody [Clone ID: 5A5]
CAT#: AM06739PU-N
PDX1 mouse monoclonal antibody, clone 5A5, Purified
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CNY 5,775.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 5A5 |
Applications | ELISA, FC, WB |
Recommend Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human PDX1 expressed in E. Coli. |
Specificity | Recognizes Insulin promoter factor 1 (PDX1) |
Formulation | PBS State: Purified State: Liquid purified antibody Stabilizer: 0.5% protein stabilizer Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 30.8 kDa |
Gene Name | pancreatic and duodenal homeobox 1 |
Database Link | |
Background | The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
Synonyms | PDX1, PDX-1, IPF1, Pancreas/duodenum homeobox protein 1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, Insulin upstream factor 1, IUF-1, Glucose-sensitive factor, GSF |
Reference Data |
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