MMP3 Mouse Monoclonal Antibody [Clone ID: 4F10]

Specifications

Product Data
Clone Name	4F10
Applications	ELISA, FC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human MMP3 expressed in E. Coli.
Specificity	This antibody reacts to MMP3.
Formulation	PBS State: Purified State: Liquid purified Ig fraction Stabilizer: 0,5% BSA Preservative: 0.05% sodium azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	54 kDa
Gene Name	matrix metallopeptidase 3
Database Link	Entrez Gene 4314 Human UniProt ID P08254
Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Synonyms	Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1
Reference Data

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