Glucose 6 Phosphate Dehydrogenase (G6PD) Mouse Monoclonal Antibody [Clone ID: 5E12]

Specifications

Product Data
Clone Name	5E12
Applications	ELISA, FC, IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human G6PD expressed in E. Coli.
Specificity	This antibody reacts to G6PD.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	59 kDa
Gene Name	glucose-6-phosphate dehydrogenase
Database Link	Entrez Gene 2539 Human UniProt ID P11413
Background	This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	Glucose-6-phosphate 1-dehydrogenase, Glucose-6-P-Dehydrogenase
Reference Data

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