ABCG2 Mouse Monoclonal Antibody [Clone ID: 3G8]
CAT#: AM06628SU-N
ABCG2 mouse monoclonal antibody, clone 3G8, Ascites
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CNY 5,775.00
货期*
5周
规格
Cited in 2 publications. |
Specifications
Product Data | |
Clone Name | 3G8 |
Applications | ELISA, FC, IF, IHC, WB |
Recommend Dilution | Western Blot: 1/500-1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000. Immunofluorescence: 1/200-1/1000. Flow Cytometry: 1/200-1/400. ELISA: 1/10000. |
Reactivity | Human, Monkey, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human ABCG2 expressed in E. Coli. |
Specificity | This antibody reacts to ABCG2. |
Formulation | State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 72 kDa |
Gene Name | ATP binding cassette subfamily G member 2 (Junior blood group) |
Database Link | |
Background | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon. |
Synonyms | Breast cancer resistance protein 1, ABCP, MXR |
Reference Data |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
Elevation of β-galactoside α2,6-sialyltransferase 1 in a fructose-responsive manner promotes pancreatic cancer metastasis
,null,
Oncotarget
,PubMed ID 28032597
[ABCG2]
|
Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue
,null,
Scientific Reports
,PubMed ID 27257141
[ABCG2]
|
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