Osteoprotegerin (TNFRSF11B) Mouse Monoclonal Antibody [Clone ID: 5G2]
CAT#: AM06539SU-N
Osteoprotegerin (TNFRSF11B) mouse monoclonal antibody, clone 5G2, Ascites
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CNY 5,346.00
货期*
5周
规格
Cited in 1 publication. |
Specifications
Product Data | |
Clone Name | 5G2 |
Applications | ELISA, FC, IF, WB |
Recommend Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow Cytometry: 1/200 - 1/400. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human TNFRSF11B expressed in E. Coli. |
Specificity | Recognizes Osteoprotegerin / TNFRSF11B |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | 60 kDa |
Gene Name | tumor necrosis factor receptor superfamily member 11b |
Database Link | |
Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
Synonyms | OPG, OCIF |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Comprehensive assessment of tissue and serum parameters of bone metabolism in a series of orthopaedic patients
,Gunsser, J;Hermann, R;Roth, A;Lupp, A;,
PLoS ONE
,PubMed ID 31881044
[TNFRSF11B]
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