B7-2 (CD86) Mouse Monoclonal Antibody [Clone ID: 1B3]

CAT#: AM06519SU-N

B7-2 (CD86) mouse monoclonal antibody, clone 1B3, Ascites



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CNY 5,346.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Clone Name 1B3
Applications ELISA, WB
Recommend Dilution ELISA: 1/10000.
Western Blot: 1/500 - 1/2000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Purified recombinant fragment of Human CD86 expressed in E. Coli.
Specificity Recognizes CD86
Formulation State: Ascites
State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size 52 kDa
Gene Name CD86 molecule
Background This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.
Synonyms CD28LG2, Activation B7-2 antigen, B70, BU63, B7.2, FUN-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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