CHD3 Mouse Monoclonal Antibody [Clone ID: 2G4]
CAT#: AM06458SU-N
CHD3 mouse monoclonal antibody, clone 2G4, Ascites
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CNY 5,346.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 2G4 |
Applications | ELISA, FC, IF, IHC, WB |
Recommend Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human CHD3 expressed in E. Coli. |
Specificity | This antibody reacts to CHD3. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 226 kDa |
Gene Name | chromodomain helicase DNA binding protein 3 |
Database Link | |
Background | This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
Synonyms | CHD-3, Mi2-alpha, Zinc finger helicase, hZFH |
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