FOXA2 Mouse Monoclonal Antibody [Clone ID: 7H4B7]

Specifications

Product Data
Clone Name	7H4B7
Applications	IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of FOXA2 expressed in E. Coli.
Specificity	This antibody reacts to FOXA2.
Formulation	State: Ascites State: Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	48 kDa
Gene Name	forkhead box A2
Database Link	Entrez Gene 3170 Human UniProt ID Q9Y261
Background	FOXA2 (forkhead box A2), also known as HNF3B (hepatocyte nuclear factor 3, beta). It is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for FOXA2.
Synonyms	HNF-3-beta, HNF-3B, TCF3B
Reference Data

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