CD44 Mouse Monoclonal Antibody [Clone ID: 8E2F3]

Specifications

Product Data
Clone Name	8E2F3
Applications	ELISA, FC, IF, IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. Flow Cytometry: 1/200-1/400. Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human CD44 (628-699) expressed in E. Coli.
Specificity	Recognizes CD44
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	82 kDa
Gene Name	CD44 molecule (Indian blood group)
Database Link	Entrez Gene 960 Human UniProt ID P16070
Background	CD44, also known as IN, LHRMIC4, CDW44, HCELL is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Synonyms	LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1
Reference Data

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