Lysyl tRNA synthetase (KARS) Mouse Monoclonal Antibody [Clone ID: 8G12C1]

Specifications

Product Data
Clone Name	8G12C1
Applications	IHC, WB
Recommend Dilution	ELISA: 1/10000. Western blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of KARS(aa90-174) expressed in E. Coli.
Specificity	Recognizes Lysyl Trna Synthetase (KARS).
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lysyl-tRNA synthetase
Database Link	Entrez Gene 3735 Human UniProt ID Q15046
Background	Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Synonyms	Lysyl-tRNA synthetase, KIAA0070, LysRS, Lysine-tRNA ligase
Reference Data

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