BIRC5 Mouse Monoclonal Antibody [Clone ID: 2H5H2]

Specifications

Product Data
Clone Name	2H5H2
Applications	WB
Recommend Dilution	ELISA: 1/10000. Western Bloting: 1/500 - 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Survivin expressed in E. Coli.
Specificity	Recognizes  Survivin
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	baculoviral IAP repeat containing 5
Database Link	Entrez Gene 332 Human UniProt ID O15392
Background	Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Synonyms	Survivin, Apoptosis inhibitor 4, API4
Reference Data

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