HCK Mouse Monoclonal Antibody [Clone ID: 3D12E10]

Specifications

Product Data
Clone Name	3D12E10
Applications	IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blotting: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of HCK expressed in E. Coli.
Specificity	Recognizes HCK
Formulation	State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	HCK proto-oncogene, Src family tyrosine kinase
Database Link	Entrez Gene 3055 Human UniProt ID P08631
Background	Hemopoietic cell kinase.The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
Synonyms	Hemopoietic cell kinase, p59-HCK, p60-HCK, BMK, p56-HCK
Reference Data

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