TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: 2A9B9]

CAT#: AM06195PU-N

TNF alpha (TNF) mouse monoclonal antibody, clone 2A9B9, Purified



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CNY 5,346.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Clone Name 2A9B9
Applications WB
Recommend Dilution ELISA: 1/10000.
Western Blotting: 1/500 - 1/2000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant Human TNF-alpha
Specificity Recognizes TNF-alpha
Formulation PBS
State: Purified
State: Liquid purified IgG fraction
Preservative: 0.03% Sodium Azide.
Conjugation Unconjugated
Storage Condition

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name tumor necrosis factor
Background TNF-alpha (tumor necrosis factor alpha) is an important cytokine produced by numerous cell types including neutrophils, activated lymphocytes, macrophages and NK cells. It plays a critical role in inflammatory responses and in apoptosis. TNF-alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF-alpha exists as a multimer of two, three, or five non covalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. Although it has little effect on many cultured normal human cells, TNF-alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF-alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF-alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
Synonyms TNF, TNF-a, TNFA, TNFSF2, Cachectin
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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