S100A1 Mouse Monoclonal Antibody [Clone ID: 2C8B8]

Specifications

Product Data
Clone Name	2C8B8
Applications	IHC, WB
Recommend Dilution	ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of S100A1 expressed in E. Coli.
Specificity	Recognizes S100 calcium binding protein A1 (S100-alpha/ S100A1).
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	S100 calcium binding protein A1
Database Link	Entrez Gene 6271 Human UniProt ID P23297
Background	S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Synonyms	S100-A1, S100A, S100 alpha, S100 calcium-binding protein A1, S-100 protein subunit alpha, S-100 protein alpha chain
Reference Data

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