GST3 (GSTP1) Mouse Monoclonal Antibody [Clone ID: 3F2C2]

Specifications

Product Data
Clone Name	3F2C2
Applications	ELISA, FC, IF, IHC, WB
Recommend Dilution	ELISA: 1/10000.  Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. Flow Cytometry: 1/200-1/400.  Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human GSTP1 expressed in E. Coli.
Specificity	Recognizes GSTP1 (glutathione-S-transferase, pi 1).
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	23 kDa
Gene Name	glutathione S-transferase pi 1
Database Link	Entrez Gene 2950 Human UniProt ID P09211
Background	GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
Synonyms	Glutathione S-transferase P, GSTP1-1, GST pi, GST class-pi, FAEES3
Reference Data

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