gamma Synuclein (SNCG) Mouse Monoclonal Antibody [Clone ID: 1H10D2]

Specifications

Product Data
Clone Name	1H10D2
Applications	IHC, WB
Recommend Dilution	Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of SNCG expressed in E. Coli.
Specificity	Recognizes SNCG (breast cancer-specific protein 1).
Formulation	Ascitic fluid containing 0.03% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	synuclein gamma
Database Link	Entrez Gene 6623 Human UniProt ID O76070
Background	SNCG (also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Synonyms	PERSYN, Synuclein gamma, Synoretin, BCSG1, PRSN
Reference Data

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