CD8A Mouse Monoclonal Antibody [Clone ID: RAVB3]

Specifications

Product Data
Clone Name	RAVB3
Applications	ELISA, FC
Recommend Dilution	Flow Cytometry: 1/200-1/400. ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human CD8 expressed in E. Coli.
Specificity	Recognizes CD8
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD8a molecule
Database Link	Entrez Gene 925 Human UniProt ID P01732
Background	CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
Synonyms	CD8 alpha chain, CD8A, MAL
Reference Data

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