Apolipoprotein A V (APOA5) Mouse Monoclonal Antibody [Clone ID: 4H8H8E2 (c)]

Specifications

Product Data
Clone Name	4H8H8E2 (c)
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/10000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human APOA5 expressed in E. Coli.
Formulation	State: Ascites State: Ascitic fluid Preservative: 0.03% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	apolipoprotein A5
Database Link	Entrez Gene 116519 Human UniProt ID Q6Q788
Background	Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglyc erides, whereas a knock-in model with human ApoA5 produced 50–70% lowerconcentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Synonyms	Apolipoprotein A-V, Apo-AV, ApoA-V, RAP3
Reference Data

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