Cytokeratin 7 (KRT7) Mouse Monoclonal Antibody [Clone ID: LP5K]

Specifications

Product Data
Clone Name	LP5K
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 1x106 cells in 100 µl. Immunohistochemistry on Frozen Sections: 1/10. Immunohistochemistry on Paraffin Sections: 1/10 (Requires protein digestion pre-treatment e.g. trypsin or pronase). Histology Positive Control: Human skin.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Cytoskeletal proteins from cultured HeLa cells
Specificity	The antibody reacts with Cytokeratin 7 which has been found in columnar and glandular epithelium of the lung, cervix, breast, bile ducts and larger collecting ducts of the kidney. Occasionally staining of blood vessel cell walls, particularly endothelial cells, may be observed.
Formulation	PBS Label: FITC State: Purified State: Liquid purified IgG fraction Stabilizer: 0.1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1
Purification	Ammonium Sulphate Precipitation followed by Ion Exchange Chromatography
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This products is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	keratin 7
Database Link	Entrez Gene 3855 Human UniProt ID P08729
Background	Cytokeratin 7 is a 54kD intermediate filament protein found in a variety of glandularepithelia. Cytokeratin 7 has been found in columnar and glandular epithelium of the lung, cervix, breast, bile ducts and larger collecting ducts of the kidney. It is present in the transitional epithelium of bladder as well as ovarian and lungepithelia, and occasionally staining of blood vessel cell walls, particularly endothelial cells, may be observed. However, Cytokeratin 7 is not expressed by epithelial cells of the gastrointestinal tract, colon or prostate. Keratin 7 is often co expressed with keratin 19.
Synonyms	KRT7, KRT-7, SCL, CK-7, CK7, Keratin-7, K7, K-7, Sarcolectin
Reference Data

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