Complement C7 (C7) Mouse Monoclonal Antibody [Clone ID: 030-113.7.5.4]

Specifications

Product Data
Clone Name	030-113.7.5.4
Applications	ELISA, FN, WB
Recommend Dilution	ELISA. Western Blot. Functional Assays: Removal of Sodium Azide is recommended prior to use.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human C7
Specificity	This antibody recognises complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. Note that this antibody does not recognise membrane bound complement membrane attack complex. This antibody inhibits lysis of sensitised sheep erythrocytes.
Formulation	Borate buffered saline pH8.2 - 8.4 containing 0.02% Sodium Azide (NaN3) State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	complement component 7
Database Link	Entrez Gene 730 Human UniProt ID P10643
Background	The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides.
Synonyms	Complement component C7, Complement 7
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.