Pdcd1 Rat Monoclonal Antibody [Clone ID: RMP1-30]

Specifications

Product Data
Clone Name	RMP1-30
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/100-1/200 diluted antibody to label 106 cells in 100 µl.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	PD-1 transferred BHK cells
Specificity	This antibody recognises CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified IgG Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	programmed cell death 1
Database Link	Entrez Gene 18566 Mouse UniProt ID Q02242
Background	CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279.
Synonyms	Protein PD-1, hPD-1, PDCD1
Reference Data

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