Osteocalcin (BGLAP) Mouse Monoclonal Antibody [Clone ID: 3H8H12D2A12F12]

Specifications

Product Data
Clone Name	3H8H12D2A12F12
Applications	ELISA
Recommend Dilution	ELISA: This antibody may be used in combination with AM05458PU-N or AM05457PU-N in sandwich ELISA assays.
Reactivity	Bovine, Human, Porcine, Rabbit, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Native bovine osteaocalcin
Specificity	This antibody recognizes intact human and bovine osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 15-31 and 20-43 of the native molecule. It does not recognize fragments representing amino acids 1-19 or 7-19 or intact bovine osteocalcin.
Formulation	Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	bone gamma-carboxyglutamate protein
Database Link	Entrez Gene 632 Human UniProt ID P02818
Background	Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.
Synonyms	Bone Gla protein, BGLAP
Reference Data

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