CYPIVF11 (CYP4F11) Mouse Monoclonal Antibody [Clone ID: F21 P6 F5]

Specifications

Product Data
Clone Name	F21 P6 F5
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1 - 2 µg/ml. Immunohistochemistry on paraffin sections: 1 - 5 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the Cterminus of the human CYP450 4F11 protein and mouse myeloma Ag8563 cells.
Specificity	This Antibody reacts to Cytochrome P450 4F11.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	cytochrome P450 family 4 subfamily F member 11
Database Link	Entrez Gene 57834 Human UniProt ID Q9HBI6
Background	The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP4F11 is an isoform of the cytochrome P450 4F protein and is expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. CYP4F11 contains 524 amino acid residues that share 80.0, 82.3 and 79.2% identity to CYP4F2, CYP4F3, and CYP4F8 amino acid sequences, respectively. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.
Synonyms	Cytochrome P450 4F11, CYPIVF11
Reference Data

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