CYP3A7-CYP3A51P Mouse Monoclonal Antibody [Clone ID: F19 P2 H2]

Specifications

Product Data
Clone Name	F19 P2 H2
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1 - 2 µg/ml. Immunohistochemistry on paraffin sections: 1 - 5 µg/ml. When used in conjunction with CYP3A5, can differentiate between the CYP3A family members, 3A5 and 3A7.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the Cterminus of the human CYP3A7 protein and mouse myeloma Ag8563 cells.
Specificity	This antibody reacts to Cytochrome P450 3A7.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	CYP3A7-CYP3A51P readthrough
Database Link	Entrez Gene 100861540 Human UniProt ID P24462
Background	CYP3A genes encode monooxygenases, enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A (cytochrome P450, family 3, subfamily A), the most abundant P450 enzyme in human liver, is responsible for the metabolism of more than 50% of all clinical drugs. CYP3A members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster consists of four genes: CYP3A43, CYP3A4, CYP3A7 and CYP3A5, and two pseudogenes: CYP3A5P1 and CYP3A5P2. The CYP3A cluster maps to gene locus 7q21.3-q22.1.
Synonyms	Cytochrome P450 3A7, CYPIIIA7, Cytochrome P450-HFLA
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.