HIRA Mouse Monoclonal Antibody [Clone ID: 10]

Specifications

Product Data
Clone Name	10
Applications	WB
Recommend Dilution	Western blot (5-10 µg/ml). Positive Control: Mav108 cells expressing recombinant TUP1 protein.
Reactivity	Saccharomyces cerevisiae
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant protein derived from the amino acids 1-200 of yeastt TUP1 protein
Formulation	PBS containing containing 0.08% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	histone cell cycle regulator
Database Link	UniProt ID P54198
Background	Yeast Tup 1p-Ssn6p repressor complex represents a novel paradigm for transcriptional repression and for the role of chromatin in repression. TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.
Synonyms	DGCR1, HIR
Reference Data

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