Rabies Virus Mouse Monoclonal Antibody [Clone ID: RV1C5]

Specifications

Product Data
Clone Name	RV1C5
Applications	ELISA, IF, IHC, Neutralize
Recommend Dilution	Detection of Rabies and Rabies related virus. Immunohistochemistry on Paraffin Sections. Indirect ELISA: 1.5x106. Immunofluorescence: Specific Titer > 1x103.
Reactivity	Rabies Lyssavirus
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Rabies virus
Specificity	Rabies Virus antibody reacts with a glycoprotein of Rabies virus. More than 20 different strains from 4 serogroups, including CVS, Lagosbat, Mokola, Duwenhage were positive in neutralization reaction.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction (>95% pure by SDS-PAGE). Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Background	Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
Reference Data

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