TNF alpha (TNF) Mouse Monoclonal Antibody [Clone ID: tnfa9.9]

Specifications

Product Data
Clone Name	tnfa9.9
Applications	ELISA, R, WB
Recommend Dilution	ELISA. RIA. Western blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Tumor Necrosis Factor alpha
Specificity	This antibody detects Tumor Necrosis Factor alpha.
Formulation	50 mM TRIS, pH 7,4 State: Purified State: Lyophilized purified IgG fraction Preservative: 0.02% Sodium Azide
Reconstitution Method	Restore in aqua bidest to 1 mg/ml.
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
Gene Name	tumor necrosis factor
Database Link	Entrez Gene 7124 Human UniProt ID P01375
Background	Tumor Necrosis Factor (TNF) is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. TNF is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Synonyms	TNF, TNF-a, TNFA, TNFSF2, Cachectin
Note	LocusID 7124
Reference Data

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