beta Defensin 3 (DEFB103A) (6-22) Mouse Monoclonal Antibody [Clone ID: L3-18b-E1]

Specifications

Product Data
Clone Name	L3-18b-E1
Applications	ELISA, IHC, R, WB
Recommend Dilution	RIA. ELISA. Western Blot (Ref.1). Immunohistochemistry Paraffin Sections: 1/50 (Ref.1).
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic Human beta-Defensin 3 (aa 6-22)
Specificity	This antibody detects Human beta-Defensin 3 (aa 6-22), Rat beta-Defensin 3.
Formulation	50 mM TRIS pH 7.4 State: Purified State: Lyophilized purified IgG fraction from Cell Culture Supernatant
Reconstitution Method	Restore in 100 µl aqua bidest to 1 mg/ml.
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	defensin beta 103A
Database Link	Entrez Gene 414325 Human UniProt ID P81534
Background	Beta Defensin 3 exhibits antimicrobial activity against Gram positive bacteria S.aureus and S.pyogenes, Gram negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. It kills multiresistant S.aureus and vancomycin resistant E.faecium, but it appears to have no significant hemolytic activity. Beta Defensin 3 is highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression is observed in salivary gland, bone marrow, colon, stomach, polyp and larynx, with no expression in small intestine. Expression is induced by infection of bacteria and by interferon gamma. Beta Defensin 3 belongs to the beta defensin family.
Synonyms	DEFB103A, DEFB103B, BD3, DEFB3, HBP3, HBD3, DEFB103, Beta-defensin 103, Defensin-like protein, Defensin beta 103
Note	GenID: 55894 and 414325
Reference Data

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