BNP (NPPB) (NT-proBNP 1-21) Mouse Monoclonal Antibody [Clone ID: 27-4-3]

Specifications

Product Data
Clone Name	27-4-3
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic human pro-BNP (aa 1-21) poly Lysin conjugated
Specificity	This antibody detects synthetic pro-BNP (aa 1-21)
Formulation	200 mM Na Citrat / TRIS, 500 mM NaCl buffer pH 7;5 0,02% NaN3 State: Purified State: Lyophilized IgG fraction
Reconstitution Method	Restore in aqua bidest to 1 mg/ml.
Purification	Protein A chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Gene Name	natriuretic peptide B
Database Link	Entrez Gene 4879 Human UniProt ID P16860
Background	In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
Synonyms	NPPB, Brain natriuretic peptide, BNP, proBNP
Reference Data

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