Properdin (CFP) Mouse Monoclonal Antibody [Clone ID: 10-24]
CAT#: AM01338PU-N
Properdin (CFP) mouse monoclonal antibody, clone 10-24, Purified
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CNY 7,678.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | 10-24 |
Applications | ELISA, IHC |
Recommend Dilution | ELISA. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Native purified factor P from human serum. |
Specificity | This antibody recognises complement factor P, a 53 kDa glycosylated protein present in blood serum. This antibody does not inhibit function of complement factor P. |
Formulation | Borate buffered saline pH 8.2 containing 0.02% Sodium Azide State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | complement factor properdin |
Database Link | |
Background | Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. |
Synonyms | CFP, PFC, Complement factor P |
Reference Data | |
Protein Families | Secreted Protein |
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