IL2RA Mouse Monoclonal Antibody [Clone ID: IL-A111]

Specifications

Product Data
Clone Name	IL-A111
Applications	FC
Recommend Dilution	Flow Cytometry: 1/10.
Reactivity	Bovine, Sheep
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises the CD25 cell surface antigen, a 55kDa glycoprotein also known as Interleukin-2 receptor alpha chain. Bovine CD25 is expressed by activated T cells.
Formulation	Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide, 1% Bovine Serum Albumin Label: PE State: Lyophilised purified IgG Label: R. Phycoerythrin (RPE)
Reconstitution Method	Reconstitute with 1 ml distilled water
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Database Link	Entrez Gene 281861 Bovine UniProt ID P12342
Background	The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.
Synonyms	Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TAC antigen
Reference Data

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