Ly86 Rat Monoclonal Antibody [Clone ID: MD113]

Specifications

Product Data
Clone Name	MD113
Applications	FC, FN
Recommend Dilution	Flow cytometry: The typical starting working dilution is 1:50. Functional assays. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Cannot be used for Western blot and immunoprecipitation.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	The monoclonal antibody MD113 reacts with mouse MD-1. The antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.
Formulation	PBS State: Purified State: Liquid 0.2 μm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein G
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Gene Name	lymphocyte antigen 86
Database Link	Entrez Gene 17084 Mouse UniProt ID O88188
Background	MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS.
Synonyms	Lymphocyte antigen 86, MD1
Reference Data

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