p75 NGF Receptor (NGFR) (1-160) Mouse Monoclonal Antibody [Clone ID: NGFR5]

Specifications

Product Data
Clone Name	NGFR5
Applications	FC
Recommend Dilution	Indirect immunofluorescence analysis by Flow cytometry: 1:200 as starting point.
Reactivity	Feline, Ferret, Human, Primate, Rabbit
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified CD271 protein isolated from human melanoma cell line A875
Specificity	This antibody recognizes CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.
Formulation	Phosphate buffered saline (PBS) Label: Biotin State: Liquid purified Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4 Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Concentration	lot specific
Conjugation	Biotin
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	nerve growth factor receptor
Database Link	Entrez Gene 4804 Human UniProt ID P08138
Background	CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
Synonyms	TNFRSF16
Reference Data

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