MEK5 (MAP2K5) (incl. pos. control) Mouse Monoclonal Antibody [Clone ID: 14B5]

CAT#: AM00095PU-N

MEK5 (MAP2K5) (incl. pos. control) mouse monoclonal antibody, clone 14B5, Purified



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CNY 5,973.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 14B5
Applications WB
Recommend Dilution Western Blot: 0.5 µg/ml for HRPO/ECL detection.
Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer.
Positive Control: Cell lysate from untreated A431 cells.
Reactivity Canine, Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Synthetic peptide conjugated to hemocyanin
Specificity This antibody reacts to MKK5.
Formulation 1 ml PBS / 0.09 % Na-azide / PEG and Sucrose
State: Purified
State: Lyophilized purified IgG
Reconstitution Method Restore with 1 ml H2O (15 min, RT).
Purification Size exclusion chromatography
Conjugation Unconjugated
Storage Condition Store lyophilized (preferably in a desiccator) at -20°C and reconstituted (aliquote and freeze in liquid nitrogen) at -80°C.
Avoid repeated freezing and thawing.
Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months.
Gene Name mitogen-activated protein kinase kinase 5
Background Mitogen-activated protein kinase kinase 5 (MKK5) belongs to the serine/threonine protein kinase family and the MAPK subfamily (MAP2K, MKK or MEKs). MKK5 specifically phosphorylates erk5/MAPK7 within the kinase activation loop pThr-E-pTyr motif. After activation erk5 phosphorylates MKK5 on multiple phosphoserine residues. The MKK5/erk5 pathway may play an important role in prostate and breast cancer.
Synonyms MAP kinase kinase 5, MAPKK 5, MEK5, MKK5
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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