beta Defensin 1 (DEFB1) (NM_005218) Human Mass Spec Standard

Specifications

Product Data
Description	DEFB1 MS Standard C13 and N15-labeled recombinant protein (NP_005209)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208244
Predicted MW	7.4 kDa
Protein Sequence	Sequence Link (showhide) >RC208244 protein sequence Red=Cloning site Green=Tags(s) MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005209
RefSeq Size	484
RefSeq ORF	204
Synonyms	BD1; DEFB-1; DEFB101; HBD1
Locus ID	1672
Cytogenetics	8p23.1
Summary	Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein

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