MPZL (MPZL1) (NM_001146191) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC228059L4V
- LentiORF®
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Lenti ORF particles, MPZL1 (mGFP-tagged)-Human myelin protein zero-like 1 (MPZL1), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | MPZL (MPZL1) (NM_001146191) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | MPZL1b; PZR; PZR1b; PZRa; PZRb |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001146191 |
ORF Size | 357 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC228059).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001146191.1 |
RefSeq ORF | 360 bp |
Locus ID | 9019 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
MW | 12.2 kDa |
Gene Summary | Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.[UniProtKB/Swiss-Prot Function] |
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