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BBS7 (NM_176824) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC224479L3V
- LentiORF®
-
Lenti ORF particles, BBS7 (Myc-DDK-tagged)-Human Bardet-Biedl syndrome 7 (BBS7), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 13,585.00
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Specifications
| Product Data | |
| Product Name | BBS7 (NM_176824) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BBS2L1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_176824 |
| ORF Size | 2145 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC224479).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_176824.1 |
| RefSeq Size | 3718 bp |
| RefSeq ORF | 2148 bp |
| Locus ID | 55212 |
| MW | 80.2 kDa |
| Gene Summary | This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy; however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014] |
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