MED1 (NM_004774) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC222118L3V
- LentiORF®
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Lenti ORF particles, MED1 (Myc-DDK tagged) - Human mediator complex subunit 1 (MED1), 200ul, >10^7 TU/mL
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CNY 11,210.00
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规格
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Specifications
Product Data | |
Product Name | MED1 (NM_004774) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CRSP1; CRSP200; DRIP205; DRIP230; PBP; PPARBP; PPARGBP; RB18A; TRAP220; TRIP2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_004774 |
ORF Size | 4743 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC222118).
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OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_004774.2 |
RefSeq Size | 5809 bp |
RefSeq ORF | 4746 bp |
Locus ID | 5469 |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
MW | 168.3 kDa |
Gene Summary | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008] |
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