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Huntingtin Associated Protein 1 (HAP1) (NM_001079870) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC220305L4V
- LentiORF®
-
Lenti ORF particles, HAP1 (mGFP-tagged)-Human huntingtin-associated protein 1 (HAP1), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 11,875.00
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Specifications
| Product Data | |
| Product Name | Huntingtin Associated Protein 1 (HAP1) (NM_001079870) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | HAP2; hHLP1; HIP5; HLP |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001079870 |
| ORF Size | 1806 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC220305).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001079870.1, NP_001073339.1 |
| RefSeq Size | 3893 bp |
| RefSeq ORF | 1809 bp |
| Locus ID | 9001 |
| Protein Pathways | Huntington's disease |
| MW | 67.4 kDa |
| Gene Summary | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
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