Endothelin 3 (EDN3) (NM_207033) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220103L3V
- LentiORF®
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Lenti ORF particles, EDN3 (Myc-DDK-tagged)-Human endothelin 3 (EDN3), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 7,410.00
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经常一起买 (3)
Specifications
Product Data | |
Product Name | Endothelin 3 (EDN3) (NM_207033) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | ET-3; ET3; HSCR4; PPET3; WS4B |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_207033 |
ORF Size | 672 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220103).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_207033.1 |
RefSeq Size | 2617 bp |
RefSeq ORF | 675 bp |
Locus ID | 1908 |
Protein Families | Druggable Genome, Secreted Protein |
MW | 21.3 kDa |
Gene Summary | The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] |
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