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GNRH2 (NM_001501) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC214336L4V
- LentiORF®
-
Lenti ORF particles, GNRH2 (mGFP-tagged) - Human gonadotropin-releasing hormone 2 (GNRH2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,360.00
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| Product Data | |
| Product Name | GNRH2 (NM_001501) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | GnRH-II; LH-RHII |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001501 |
| ORF Size | 360 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC214336).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001501.1 |
| RefSeq Size | 423 bp |
| RefSeq ORF | 363 bp |
| Locus ID | 2797 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | GnRH signaling pathway |
| MW | 12.9 kDa |
| Gene Summary | This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleaved to form neuropeptides which, in part, regulate reproductive functions by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The human GNRH2 gene is predicted to encode a preproprotein from which a mature neuropeptide of 10 amino acids is cleaved. However, while the human genome retains the sequence for a functional GNRH2 decapeptide, translation of the human GNRH2 gene has not yet been demonstrated and the GNRH2 gene of chimpanzees, gorilla, and Sumatran orangutan have a premature stop at codon eight of the decapeptide sequence which suggests GNRH2 was a pseudogene in the hominid lineage. The GNRH2 gene is also believed to be a pseudogene in many other mammalian species such as mouse and cow. The receptor for this gene (GNRHR2) is predicted to be a pseudogene in human as well as many other mammalian species. The closely related GNRH1 and GNRHR1 genes are functional in human and other mammals and are generally functional in vertebrates. [provided by RefSeq, Mar 2019] |
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