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USP51 (NM_201286) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC214303L2V
- LentiORF®
-
Lenti ORF particles, USP51 (mGFP-tagged) - Human ubiquitin specific peptidase 51 (USP51), 200ul, >10^7 TU/mL
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CNY 15,010.00
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Specifications
| Product Data | |
| Product Name | USP51 (NM_201286) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-mGFP |
| ACCN | NM_201286 |
| ORF Size | 2133 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC214303).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_201286.2 |
| RefSeq Size | 2490 bp |
| RefSeq ORF | 2136 bp |
| Locus ID | 158880 |
| Protein Families | Druggable Genome, Protease |
| MW | 79.6 kDa |
| Gene Summary | Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).[UniProtKB/Swiss-Prot Function] |
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